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ステロイド減量剤としてのCBD
CBDは、ステロイドに代わる、あるいはその用量を減少させる画期的な療法になり得るでしょうか?
CBD/大麻と自己免疫性疾患に関する科学論文:
- CBD inhibits growth and induces programmed cell death in kaposi sarcoma-associated herpes virus-infected endothelium
- Cannabidiol for the Prevention of Graft-versus-Host-Disease after Allogeneic Hematopoietic Cell Transplantation: Results of a Phase II Study.
- Cannabinoids Reduce Inflammation but Inhibit Lymphocyte Recovery in Murine Models of Bone Marrow Transplantation.
- High on Cannabis and Calcineurin Inhibitors: A Word of Warning in an Era of Legalized Marijuana.
- Targeting cannabinoid receptors as a novel approach in the treatment of graft-versus-host disease: evidence from an experimental murine model.
- Cannabidiol Limits T Cell-Mediated Chronic Autoimmune Myocarditis: Implications to Autoimmune Disorders and Organ Transplantation.
- A Case Report of the Benefit of Cannabidiol (Cannabidiol (CBD)-Predominant Medical Cannabis Preparation) in the Management of Refractory Skin Graft Vs Host Disease (GVHD)
- The cannabinoid quinol VCE-004.8 alleviates bleomycin-induced scleroderma and exerts potent antifibrotic effects through peroxisome proliferator-activated receptor-γ and CB2 pathways.
- VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPARγ- and CB2 receptor-dependent pathways.
- Cannabinoid derivatives acting as dual PPARγ/CB2 agonists as therapeutic agents for systemic sclerosis.
- Cannabis sativa as a Potential Treatment for Systemic Sclerosis.
- Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System.
- Medical cannabis: Another piece in the mosaic of autoimmunity?
- The endocannabinoid system of the skin. A potential approach for the treatment of skin disorders.
- Targeting the Cannabinoid Pathway Limits the Development of Fibrosis and Autoimmunity in a Mouse Model of Systemic Sclerosis
- Inactivation of fatty acid amide hydrolase exacerbates experimental fibrosis by enhanced endocannabinoid-mediated activation of CB1.
- Cannabinoids inhibit fibrogenesis in diffuse systemic sclerosis fibroblasts.
- EHP-101, an oral formulation of the cannabidiol aminoquinone VCE-004.8, alleviates bleomycin-induced skin and lung fibrosis.