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大麻で悪心を抑える
精神作用のないカンナビノイド、CBDは、セロトニンを分泌する受容体に作用し、比較的低用量で悪心(吐き気)と嘔吐…
カンナビノイド悪阻症候群(CHS)
大麻使用の副作用の一つ、カンナビノイド悪阻症候群について、イーサン・ルッソ博士に伺いました。
CBD/大麻と悪心に関する科学論文:
- Regulation of nausea and vomiting by cannabinoids and the endocannabinoid system
- CBD, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus
- Cannabidiolic acid prevents vomiting in Suncus murinus and nausea-induced behaviour in rats by enhancing 5-HT1A receptor activation
- Interaction between non-psychotropic cannabinoids in marihuana: effect of cannabigerol (CBG) on the anti-nausea or anti-emetic effects of cannabidiol (CBD) in rats and shrews
- Regulation of nausea and vomiting by cannabinoids
- CBD: its synthetic dimethylheptyl homolog suppress nausea in an experimental model with rats
- Preliminary efficacy and safety of an oromucosal standardized cannabis extract in chemotherapy-induced nausea and vomiting
- Effect of combined oral doses of THC & CBDA on acute and anticipatory nausea in rat models
- Motion sickness, stress and the endocannabinoid system
- Dexamethasone alleviates motion sickness in rats in part by enhancing the endocannabinoid system