This week’s newsletter covers the latest research and journalism on plant medicine, including the cognitive benefits of daily cannabis use in middle age, new CBD studies on liver cancer and skin protection, alarming findings about synthetic cannabinoids in teen vapes, a clinical trial comparing LSD doses for depression, and a tribute to an unsung hero of botanical CBD.
Noteworthy Read
The Benefits of Daily Cannabis for the Middle-Aged Brain (Psychology Today)
This article reviews recent research suggesting that regular, low-dose cannabis use may support cognitive function, reduce inflammation, and improve mood in middle-aged adults—though it emphasizes the importance of dosage and individual variability.
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Research Round-Up
CBD as a Potential Treatment for Liver Cancer (Cancer Cell International)
A recent study highlights cannabidiol’s (CBD) ability to inhibit tumor growth and promote cancer cell death in liver cancer models, supporting its promise as a complementary therapeutic agent.
The Role of Cannabis in Modulating Alzheimer’s Disease (Asian Journal of Biotechnology and Bioresource Technology)
This review explores how cannabinoids may interact with key mechanisms in Alzheimer’s pathology, including inflammation and neurodegeneration, pointing toward new therapeutic possibilities.
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CBD May Protect Skin from Sun Damage (Journal of the American Academy of Dermatology)
A new study suggests topical CBD could help mitigate UV-induced skin damage by reducing inflammation and oxidative stress, though further clinical testing is needed.
Synthetic Storm: What’s in Your Teen’s Vape That’s Alarming Scientists (Science Daily)
Researchers are raising concerns over unregulated synthetic cannabinoids and additives in teen vape products, which may pose serious neurological and cardiovascular risks.
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High-Dose Versus Low-Dose LSD Therapy for Major Depression (Cell Press Journal)
A new clinical trial compares different LSD dosages in treating major depressive disorder, finding both effective, but with distinct safety profiles and therapeutic windows.
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More Noteworthy Reading
Remembering Wade Laughter: The Unsung Hero of CBD (Project CBD)
Wade Laughter passed away recently after a long battle with cancer. Beloved within the cannabis community as the modest, softspoken horticulturist with a big heart and a great last name, Wade is one of the unsung heroes of botanical CBD that took root in northern California in the early 2010s.
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A heartfelt thank you to the CBD brands whose generous support makes it possible for Project CBD to bring you meaningful coverage of emerging plant medicine research week after week. We’re grateful for every one of you.



