This week’s newsletter covers the fallout from ICE raids on California cannabis farms, new research on CBD’s interactions with phenobarbital, and a range of studies exploring how psychedelics affect the brain, aging, and eating disorders.

Noteworthy Read

ICE Raids Reveal Cannabis Industry Resentments (MJBizDaily)

A recent ICE raid on unlicensed cannabis operations in California, tied to major operator Glass House, left one worker dead and has sparked deep industry concern. The crackdown underscores persistent resentment toward large operators and highlights the harsh realities faced by undocumented workers. The incident has reignited conversations about labor exploitation, immigration enforcement, and equity in cannabis enforcement.

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More Noteworthy Reading

ICE Raids on Cannabis Farms Intensify Debate (CalMatters)

The recent ICE raids on cannabis farms are intensifying debate over labor practices, immigration policy, and the cannabis industry’s fractured regulatory landscape.

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Research Round-Up

CBD Potentiates Phenobarbital-Induced Cell Death in Developing Brain (Science Direct)

A new preclinical study suggests that CBD may increase the neurotoxic effects of phenobarbital in developing brains, raising concerns about the concurrent use of these substances during early stages of life.

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How MDMA Rewires Serotonin and Oxytocin Systems in the Brain (PsyPost)

Researchers have uncovered new insights into how MDMA alters brain function, demonstrating significant changes in the serotonin and oxytocin signaling systems. These alterations may help explain MDMA’s prosocial and therapeutic effects, particularly in contexts like PTSD treatment.

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More than Serotonin: How Psychedelics Engage the Whole Brain (Neuroscience News)

Emerging research reveals that psychedelics such as LSD and psilocybin act on multiple brain networks, not just serotonin receptors. The study highlights their influence on brain-wide connectivity, suggesting broader mechanisms underlying their effects.

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Slowing Aging: Psilocybin Helps Extend Life Span in Human Cells (Medical News Today)

A recent study finds that psilocybin can delay senescence in human skin cells, potentially extending their life span. The results hint at potential anti-aging applications for psychedelics, though further research is needed to translate these findings into practice.

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Psychedelics for Eating Disorders (PubMed)

A systematic review of existing literature explores the potential of psychedelics as treatments for eating disorders. Preliminary findings suggest that substances like psilocybin may improve psychological flexibility and reduce symptoms, but controlled clinical trials remain limited.

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A heartfelt thank you to all of the CBD brands whose generous support makes it possible for Project CBD to shine a light on the latest plant medicine research — your commitment to this work truly matters.

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