This week’s newsletter covers the latest research and journalism on plant medicine, including the long-term mental health benefits of psychedelic experiences, CBN’s neuroprotective potential, the endocannabinoid system’s role in antidepressant effects, safety concerns in psychedelic therapy, and the use of cannabis for athletes and stroke recovery.
Noteworthy Read
Psychedelic Experiences Linked to Long-Term Mental Health Improvements (PsyPost)
A new study finds that individuals who report profound psychedelic experiences—especially those characterized by ego dissolution—often show lasting increases in psychological flexibility, which is associated with better mental health outcomes. Read more
View more in Psychedelics
More Noteworthy Reading
Is the Drug Doing Something or Is It All in the Mind? A Deep Dive into Microdosing (Project CBD)
Is the drug doing something or is it all in the mind? A deep dive into the trend of microdosing by Nate Seltenrich.
View more in Psychedelics
Review: Psychedelic Justice: Toward a Diverse and Equitable Psychedelic Culture
A review of ‘Psychedelic Justice: Toward a Diverse and Equitable Psychedelic Culture’ edited by Beatriz Labate and Clancy Cavnar.
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Research Round-Up
Preclinical Study: CBN vs. Age-Related Decline (PubMed)
Cannabinol (CBN) may help counteract age-related cognitive and motor decline, according to a preclinical study in mice, highlighting its neuroprotective potential. Read more
View more in Endocannabinoid System
Growing Hemp for CBD Production in China (Frontiers)
This article reviews agronomic practices, policy developments, and challenges facing China’s fast-growing hemp cultivation sector, particularly for CBD production. Read more
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Pharma Antidepressant Effects Linked to Endocannabinoid System Changes (Science Direct)
New research suggests that conventional antidepressants may exert part of their therapeutic effect by altering the endocannabinoid system, offering new targets for drug development. Read more
View more in Endocannabinoid System
Psychedelic Therapist Sexual Misconduct and Other Adverse Experiences Among Users (Psychedelic Medicine)
A study documents incidents of sexual misconduct and other adverse experiences reported by psychedelic users, raising urgent concerns about safety and oversight in underground and above-ground therapeutic settings. Read more
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Medical Cannabis for Athletes (Nutrients)
This review explores the use of medical cannabis to manage pain, inflammation, and recovery in athletic populations, while emphasizing the need for clearer regulations and research. Read more
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Effects of Cannabinoids on Ischemic Stroke-Associated Neuroinflammation (PubMed)
Cannabinoids show promise in mitigating neuroinflammatory damage following ischemic stroke, according to this study, suggesting a potential role in post-stroke recovery. Read more
View more in Endocannabinoid System
A heartfelt thank you to the CBD brands whose generous support allows Project CBD to keep shining a light on the most important developments in plant medicine research — we couldn’t do this work without you.
