This week’s newsletter covers growing concerns over synthetic cannabinoid use among teens in Ireland and the U.S., new research on CBD’s antidepressant potential and hemp seed compounds, and a wave of state-level actions targeting unregulated hemp-derived THC products.
Noteworthy Read
Teens Presenting at EDs with Psychosis from Legal Semi-Synthetic Cannabis Products (Irish Times)
Irish health officials report a rise in emergency cases of adolescent psychosis linked to legal, semi-synthetic cannabis vape products, raising concerns over regulation and youth access. While the association between cannabis and psychosis is complex and not fully understood, some research suggests that early and frequent use of potent THC products may increase the risk of psychiatric symptoms in vulnerable individuals. The rise of synthetic cannabinoids, which are often more potent and less studied than naturally occurring compounds, adds another layer of uncertainty.
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More Noteworthy Reading
Young Adults More Likely to Consume Delta-8 THC Products Where Cannabis Is Illegal (NORML)
An analysis shows that young adults are significantly more likely to use unregulated Delta-8 THC products in states where cannabis remains illegal, suggesting prohibition may drive demand for alternatives.
A Novel Insight into the Antidepressant Effect of CBD (International Journal of Neuropharmacology)
This study uncovers a new potential mechanism through which CBD may exert antidepressant effects, contributing to the growing evidence base supporting its use in mood disorder treatment.
Plant-Derived Compounds in Hemp Seeds (Molecules)
A recent study identifies a variety of bioactive compounds in hemp seeds, including polyphenols and flavonoids, which may offer antioxidant, anti-inflammatory, and other health benefits.
Florida Senate Votes Unanimously to Restrict Hemp-Derived THC (Ganjapreneur)
The Florida Senate has unanimously approved legislation to restrict the sale of hemp-derived THC products like Delta-8, citing safety concerns and calls for stronger regulation.
Hawaii Lawmakers Trying to Shut Down Illegal Dispensaries Selling Intoxicating Hemp Products (Ganjapreneur)
Hawaii legislators are pushing to close unlicensed dispensaries selling intoxicating hemp products, warning that they pose health risks and undermine the state’s regulated cannabis program.
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Michigan Cannabis Regulators Considering Vape Recycling Program (Ganjapreneur)
Michigan officials are exploring a statewide vape recycling initiative to address the growing environmental impact of disposable cannabis vape products.
Maryland to Automatically Shield Criminal Records Associated with Low-Level Cannabis Convictions (Ganjapreneur)
Maryland will begin automatically shielding records of certain low-level cannabis offenses, a move aimed at reducing barriers to housing, employment, and education for affected individuals.
Research Round-Up
California Lab Tests Expose Massive Fraud, Illegal Products & the Cannabis Equivalent of Ultra-Processed Junk Food (Project CBD)
A new study from an industry advocacy group in California examines the content of dozens of unregulated intoxicating “hemp” products that are easily available in the Golden State despite being banned by state law.
The study’s findings indicate that many so-called hemp products are infused with synthetic psychoactive cannabinoids, which can actually make users feel loopier than natural Delta-9 THC. What’s more, synthesized Delta-9 THC is present in many of these products, despite being prohibited in both California’s cannabis and hemp programs. And finally, these products, mostly vended through websites, are effectively dodging the taxman — raising no revenues for state or local governments.
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A heartfelt thank you to all of the CBD brands whose generous support allows Project CBD to keep shining a light on the latest plant medicine research and journalism. We couldn’t do this work without you.



