From the Project CBD Archives:
Project CBD talks with Dr. Bonni Goldstein about whole plant cannabis remedies, nonintoxicating cannabinoids, and cancer care for children.
Greg Gerdeman discusses brain science, the neurobiology of stress, and the ECS.
Anecdotal data indicates that CBD may be an effective treatment for stress and anxiety.
Excerpted from “Smoke Signals: A Social History of Marijuana – Medical, Recreational, and Scientific” by Martin A. Lee.
Scientific Research on CBD & Cannabis for Stress:
- Endogenous cannabinoid signaling is essential for stress adaptation
- Regulation of endocannabinoid signaling by stress: Implications for stress-related affective disorders
- Functional interactions between stress and the endocannabinoid system: from synaptic signaling to behavioral output
- Neuromodulators, stress and plasticity: a role for endocannabinoid signaling
- Downregulation of endocannabinoid signaling in the hippocampus following chronic unpredictable stress
- Endocannabinoids and stress
- Stress regulates endocannabinoid-CB1 receptor signaling
- Chronic Stress Impairs α1-Adrenoceptor-Induced Endocannabinoid-Dependent Synaptic Plasticity in the Dorsal Raphe Nucleus
- Endocannabinoid-mediated modulation of stress responses: Physiological and pathophysiological significance
- Cannabinoid receptor activation prevents the effects of chronic mild stress on emotional learning and LTP in a rat model of depression
- Cannabinoids ameliorate impairments induced by chronic stress to synaptic plasticity and short-term memory
- The anxiolytic effect of CBD on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system
- Low-frequency stimulation evokes serotonin release in the nucleus accumbens and induces long-term depression via production of endocannabinoid