Cutting-edge reporting on CBD and cannabis medicine since 2010
Beta-Caryophyllene: Terpene Powerhouse
A compound in black pepper, cinnamon, cloves, and many cannabis varietals acts on several targets that impact the endocannabinoid system.Keep reading
Is CBD Toxic to the Liver?
And did cannabidiol really kill four-and-a-half mice?Read Story
Gut Microbiota & the Endocannabinoid System
Scientific research shows that THC and CBD promote a healthy microbiome.Read Story
Delta-8, Delta-10, HHC, THCO… A Pandora’s Box of Unregulated Cannabinoids
Cannabis industry trade group declares nationwide sale of hemp-derived intoxicants a “public health disaster.”Read Story
Endocannabinoid Discovery Timeline
25 years of groundbreaking research — an annotated history.Read Story
Statins Dysregulate the Endocannabinoid System
Statin drugs cause muscle weakness and pain by suppressing cannabinoid receptor genes.Read Story
Luther Burbank, Cannabis & Me
The life and times of a CBD-rich garden in Northern California.Read Story
About Project CBD:
A garden of educational delights
Project CBD is the original and longest-running online resource for information about both CBD and medical cannabis. Established in 2010, Project CBD was instrumental in introducing CBD to the medical marijuana community in California, and it spread from there, culminating in the passage of the 2018 Farm Bill, which legalized hemp cultivation and CBD commerce in the United States. A platform for scientists, health professionals, career journalists, and drug reform activists, Project CBD serves as a centralized hub of research and writing about cannabinoid science, plant medicine, psychedelics, sustainable economies, and drug policy. We provide ways for consumers to identify and find high quality, artisanal, CBD-rich products — and ways for ethical businesses operating in the CBD and cannabis industries to be discovered by consumers.
CBD, Cannabis & Health Conditions
In our 13 years of operation, Project CBD has consolidated a large volume of peer-reviewed studies, analyses, and research on the medical uses of cannabinoids.
We have archived this information by condition and summarized the findings where possible to make the information more accessible to non-scientists. Browse by condition to learn more about the therapeutic potential of CBD and cannabis. Our website should not be considered as a source of medical advice, but as a place to discover and compare vetted studies and research.
Medical Uses of CBD & Cannabis: An Introduction →
Over 250 peer-reviewed science reports on CBD and cannabis for cancer, patient surveys, and more.
Over 350 science reviews and research papers on Alzheimer’s, Parkinson’s, MS, ALS & Huntington’s disease.
More health conditions
Cannabidiol (CBD) is a naturally occurring compound found in the resinous flower of cannabis, a plant with a rich history as a medicine going back thousands of years. Today the therapeutic properties of CBD are being tested and confirmed by scientists and doctors around the world. A safe, non-addictive substance, CBD is one of more than a hundred “phytocannabinoids,” which are unique to cannabis and endow the plant with its robust therapeutic profile.
CBD & THC
CBD is closely related to another important medicinally active phytocannabinoid: tetrahydrocannabinol (THC), the compound that causes the “high” that cannabis is famous for. These are the two components of cannabis that have been most studied by scientists.
Both CBD and THC have significant therapeutic attributes. But unlike THC, CBD does not make a person feel “stoned” or intoxicated. That’s because CBD and THC act in different ways on different receptors in the brain and body.
CBD can actually lessen or neutralize the psychoactive effects of THC, depending on how much of each compound is consumed. Many people want the health benefits of cannabis without the high – or with less of a high. The fact that CBD is therapeutically potent as well as non-intoxicating, and easy to take in various forms, makes it an appealing treatment option for those who are cautious about trying cannabis for the first time. Many people are seeking alternatives to pharmaceuticals with harsh side effects – medicine more in sync with natural processes.
By tapping into how we function biologically on a deep level, CBD can provide relief for chronic pain, anxiety, inflammation, depression and many other conditions.
Best Ways to Take CBD
Unsure about how to use CBD and cannabis? Find out the best way of taking CBD to meet your needs.
High dose? Low dose? CBD? THC? Optimizing your medical use of cannabis may entail some experimentation.
CBD Buying Tips
Recommendations for finding high-quality products.
Myths about CBD
CBD MYTH #1:
“CBD is medical. THC is recreational.”
Project CBD receives many inquiries from around the world and oftentimes people say they are seeking “CBD, the medical part” of the plant, “not THC, the recreational part” that gets you high. Actually, THC, “The High Causer,” has awesome therapeutic properties. We have published numerous articles about this that you can find in our archives.
CBD MYTH #2:
“THC is the bad cannabinoid.
CBD is the good cannabinoid.”
The drug warrior’s strategic retreat: Give ground on CBD while continuing to demonize THC. Diehard marijuana prohibitionists are exploiting the good news about CBD to further stigmatize high-THC cannabis, casting tetrahydrocannabinol as the bad cannabinoid, whereas CBD is framed as the good cannabinoid. Why? Because CBD doesn’t make you feel high like THC does. Project CBD categorically rejects this moralistic, reefer madness dichotomy in favor of whole plant cannabis therapeutics.
CBD MYTH #3:
“CBD is most effective without THC.”
THC and CBD are the power couple of cannabis compounds—they work best together. Scientific studies have established that CBD and THC interact synergistically to enhance each other’s therapeutic effects. British researchers have shown that CBD potentiates THC’s anti-inflammatory properties in an animal model of colitis. Scientists at the California Pacific Medical Center in San Francisco determined that a combination of CBD and THC has a more potent anti-tumoral effect than either compound alone when tested on brain cancer and breast cancer cell lines. And extensive clinical research has demonstrated that CBD combined with THC is more beneficial for neuropathic pain than either compound as a single molecule.